Zebrafish Models of Diamond-Blackfan Anemia: A Tool for Understanding the Disease Pathogenesis and Drug Discovery

• Main Authors: Tamayo Uechi (Author), Naoya Kenmochi (Author)
• Formato: Libro
• Publicado: MDPI AG, 2019-10-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Diamond-Blackfan anemia (DBA) is a rare bone marrow failure syndrome characterized by red blood cell aplasia. Currently, mutations in 19 ribosomal protein genes have been identified in patients. However, the pathogenic mechanism of DBA remains unknown. Recently, several DBA models were generated in...