Two-Stage Revision Arthroplasty for Resistant Gram-Positive Periprosthetic Joint Infections Using an Oral Linezolid-Based Antibiotic Regime

• Main Authors: Lars Gründer (Author), Sebastian Bockholt (Author), Georg Gosheger (Author), Martin Schulze (Author), Jan Schwarze (Author), Jan Pützler (Author), Burkhard Moellenbeck (Author), Christoph Theil (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Increasing antibiotic resistance has been reported as an issue in the systemic treatment of periprosthetic joint infection (PJI). Linezolid offers the advantages of high oral bioavailability and little resistance; however, efficacy in the treatment of PJI varies considerably, and studies...