Novel tetrazole and cyanamide derivatives as inhibitors of cyclooxygenase-2 enzyme: design, synthesis, anti-inflammatory evaluation, ulcerogenic liability and docking study
Nineteen new compounds containing tetrazole and/or cyanamide moiety have been designed and synthesised. Their structures were confirmed using spectroscopic methods and elemental analyses. Anti-inflammatory activity for all the synthesised compounds was evaluated in vivo. The most active compounds 4c...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Taylor & Francis Group,
2017-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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