Survival bias and drug interaction can attenuate cross-sectional case-control comparisons of genes with health outcomes. An example of the kinesin-like protein 6 (<it>KIF6</it>) Trp719Arg polymorphism and coronary heart disease

<p>Abstract</p> <p>Background</p> <p>Case-control studies typically exclude fatal endpoints from the case set, which we hypothesize will substantially underestimate risk if survival is genotype-dependent. The loss of fatal cases is particularly nontrivial for studies of...

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Main Authors: Pendyala Lakshmana (Author), Williams Paul (Author), Superko Robert (Author)
Format: Book
Published: BMC, 2011-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available