Thermal Analysis Study of Antihypertensive Drugs Telmisartan and Cilazapril

Purpose: The aim of the present work is to study the thermal analysis of telmisartan and cilazapril. Methods: Thermogravimetry (TGA), derivative thermogravimetry (DTG) and differential thermal analysis (DTA) were used through the work to achieve the thermal analysis study of some antihypertensive dr...

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Bibliographic Details
Main Authors: Refaat Ahmed Saber (Author), Ali Kamal Attia (Author), Waheed Mohamed Salem (Author)
Format: Book
Published: Tabriz University of Medical Sciences, 2014-05-01T00:00:00Z.
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001 doaj_957c9fd03dab4ef888fd3cb6e7b80eb1
042 |a dc 
100 1 0 |a Refaat Ahmed Saber  |e author 
700 1 0 |a Ali Kamal Attia  |e author 
700 1 0 |a Waheed Mohamed Salem  |e author 
245 0 0 |a Thermal Analysis Study of Antihypertensive Drugs Telmisartan and Cilazapril 
260 |b Tabriz University of Medical Sciences,   |c 2014-05-01T00:00:00Z. 
500 |a 10.5681/apb.2014.041 
500 |a 2228-5881 
500 |a 2251-7308 
520 |a Purpose: The aim of the present work is to study the thermal analysis of telmisartan and cilazapril. Methods: Thermogravimetry (TGA), derivative thermogravimetry (DTG) and differential thermal analysis (DTA) were used through the work to achieve the thermal analysis study of some antihypertensive drugs, telmisartan and cilazapril. Results: The results led to thermal stability data and also to the interpretation concerning the thermal decomposition. Thermogravimetry data allowed determination of the kinetic parameters such as, activation energy and frequency factor. Conclusion: The simplicity, speed and low operational costs of thermal analysis justify its application in the quality control of pharmaceutical compounds for medications. 
546 |a EN 
690 |a Telmisartan 
690 |a Cilazapril 
690 |a Antihypertensive 
690 |a Drugs 
690 |a Quality control 
690 |a Thermal analysis 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Advanced Pharmaceutical Bulletin, Vol 4, Iss 3, Pp 283-287 (2014) 
787 0 |n http://journals.tbzmed.ac.ir/APB/Abstract/APB_450_20130907181414 
787 0 |n https://doaj.org/toc/2228-5881 
787 0 |n https://doaj.org/toc/2251-7308 
856 4 1 |u https://doaj.org/article/957c9fd03dab4ef888fd3cb6e7b80eb1  |z Connect to this object online.