Different sulfonylureas induce the apoptosis of proximal tubular epithelial cell differently via closing KATP channel

• Main Authors: Rui Zhang (Author), Xiaojun Zhou (Author), Xue Shen (Author), Tianyue Xie (Author), Chunmei Xu (Author), Zhiwei Zou (Author), Jianjun Dong (Author), Lin Liao (Author)
• Format: Book
• Published: BMC, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Sulfonylureas (SUs) are widely prescribed for the treatment of type 2 diabetes (T2DM). Sulfonylurea receptors (SURs) are their main functional receptors. These receptors are also found in kidney, especially the tubular cells. However, the effects of SUs on renal proximal tubular...