The OX40 Axis is Associated with Both Systemic and Local Involvement in Atopic Dermatitis

• Main Authors: Julie Sophie Elsner (Author), Michael Carlsson (Author), Julie Kristine Stougaard (Author), Uffe Nygaard (Author), Matthias Buchner (Author), Regina Fölster-Holst (Author), Malene Hvid (Author), Christian Vestergaard (Author), Mette Deleuran (Author), Bent Deleuran (Author)
• Format: Book
• Published: Medical Journals Sweden, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atopic dermatitis (AD) is a chronic, or chronically relapsing, inflammatory skin disease associated with asthma and allergic rhinitis, and is dominated by Th2 cells. The co-stimulatory T-cell receptor OX40 and its ligand, OX40L, play a central role in the pathogenesis of AD, as their interactions ar...