Heparin-induced thrombocytopenia after MitraClip: A case report

Heparin-induced thrombocytopenia (HIT) and heparin-induced thrombocytopenia and thrombosis are potentially fatal adverse reactions to heparin therapy caused by the formation of polyclonal antibodies against the platelet factor 4-heparin complex. Fatal limb and organ damage or death may occur as a re...

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Bibliographic Details
Main Authors: Özge Çetinarslan (Author), Ümit Yaşar Sinan (Author), Emir Barış Ökçün (Author), Cengiz Çeliker (Author), Nuh Nazmi Gültekin (Author)
Format: Book
Published: KARE Publishing, 2018-03-01T00:00:00Z.
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Summary:Heparin-induced thrombocytopenia (HIT) and heparin-induced thrombocytopenia and thrombosis are potentially fatal adverse reactions to heparin therapy caused by the formation of polyclonal antibodies against the platelet factor 4-heparin complex. Fatal limb and organ damage or death may occur as a result of this immunological drug reaction. Described in this case report is the management of a patient who developed HIT after undergoing a MitraClip transcatheter mitral valve repair. The aim was to encourage clinicians to pay special attention to a frail patient who receives heparin therapy and to advise clinicians that clinical scores and laboratory tests should be used as a complement for certain diagnosis. The decision about continuation or cessation of heparin therapy is an important cornerstone for hospitalized patients with HIT.
Item Description:1016-5169
10.5543/tkda.2017.76666