Extravasation of biodegradable microspheres in the rat brain

• Autores principales: Anne-Eva van der Wijk (Autor), Theodosia Georgakopoulou (Autor), Rob Steendam (Autor), Johan Zuidema (Autor), Peter L. Hordijk (Autor), Erik N.T.P. Bakker (Autor), Ed van Bavel (Autor)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

AbstractDrug development for neurological diseases is greatly impeded by the presence of the blood-brain barrier (BBB). We and others previously reported on extravasation of micrometer-sized particles from the cerebral microcirculation - across the BBB - into the brain tissue over the course of seve...