Genetic polymorphism in Methylenetetrahydrofolate Reductase chloride transport protein 6 (MTHFR CLCN6) gene is associated with keratinocyte skin cancer in a cohort of renal transplant recipients

• Main Authors: L. Griffin (Author), L. Ho (Author), R. J. Akhurst (Author), S. T. Arron (Author), J. M. E. Boggs (Author), P. Conlon (Author), P. O'Kelly (Author), A. E. Toland (Author), E. H. Epstein (Author), A. Balmain (Author), B. C. Bastian (Author), F. J. Moloney (Author), G. M. Murphy (Author), M. E. Laing (Author)
• Format: Book
• Published: Wiley, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Renal transplant recipients (RTRs) are at increased risk of keratinocyte cancer (KC), especially cutaneous squamous cell carcinoma (cSCC). Previous studies identified a genetic variant of the Methylenetetrahydrofolate Reductase (MTHFR) gene, C677T, which conferred a risk for diag...