Identification of a New Integration Site and Study on Site-Specific Integration in CHO-K1 Cells
Site-specific integration is an important approach used to address the problem of unstable cell lines in industry. In this study, we observed a reduction in the gene copy number and antibody production in a CHOK1 cell line BA03 capable of high antibody expression. We identified a new integration sit...
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Main Authors: | Hong Liu (Author), Wei Zhang (Author), Liping Xie (Author), Youjia Hu (Author) |
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Format: | Book |
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MDPI AG,
2023-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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