Changes in Rosuvastatin Pharmacokinetics During Postnatal Ontogenesis in Rats

Purpose: Statin therapy should be considered in children with familial hypercholesterolemia and sustained high LDL-C levels. There are no data on rosuvastatin exposure in patients <6 years and efficacy/safety can only be derived from case reports. Our aim was to examine developmental changes in p...

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Main Authors: Jaroslava Roušarová (Author), Martin Šíma (Author), Petr Kozlík (Author), Tomáš Křížek (Author), Ondřej Slanař (Author)
Format: Book
Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
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