Expanding the Diversity at the C-4 Position of Pyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-ones to Achieve Biological Activity against ZAP-70

• Main Authors: Victor Masip (Author), Ángel Lirio (Author), Albert Sánchez-López (Author), Ana B. Cuenca (Author), Raimon Puig de la Bellacasa (Author), Pau Abrisqueta (Author), Jordi Teixidó (Author), José I. Borrell (Author), Albert Gibert (Author), Roger Estrada-Tejedor (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2021-12-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Pyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-ones have attracted widespread interest due to their similarity with nitrogenous bases found in DNA and RNA and their potential applicability as tyrosine kinase inhibitors. Such structures, presenting up to five diversity centers, ha...