Logic Gates Based on DNA Aptamers

DNA bio-computing is an emerging trend in modern science that is based on interactions among biomolecules. Special types of DNAs are aptamers that are capable of selectively forming complexes with target compounds. This review is devoted to a discussion of logic gates based on aptamers for the purpo...

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Bibliographic Details
Main Authors: Mariia Andrianova (Author), Alexander Kuznetsov (Author)
Format: Book
Published: MDPI AG, 2020-11-01T00:00:00Z.
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100 1 0 |a Mariia Andrianova  |e author 
700 1 0 |a Alexander Kuznetsov  |e author 
245 0 0 |a Logic Gates Based on DNA Aptamers 
260 |b MDPI AG,   |c 2020-11-01T00:00:00Z. 
500 |a 10.3390/ph13110417 
500 |a 1424-8247 
520 |a DNA bio-computing is an emerging trend in modern science that is based on interactions among biomolecules. Special types of DNAs are aptamers that are capable of selectively forming complexes with target compounds. This review is devoted to a discussion of logic gates based on aptamers for the purposes of medicine and analytical chemistry. The review considers different approaches to the creation of logic gates and identifies the general algorithms of their creation, as well as describes the methods of obtaining an output signal which can be divided into optical and electrochemical. Aptameric logic gates based on DNA origami and DNA nanorobots are also shown. The information presented in this article can be useful when creating new logic gates using existing aptamers and aptamers that will be selected in the future. 
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690 |a Medicine 
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690 |a Pharmacy and materia medica 
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655 7 |a article  |2 local 
786 0 |n Pharmaceuticals, Vol 13, Iss 11, p 417 (2020) 
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787 0 |n https://doaj.org/toc/1424-8247 
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