Logic Gates Based on DNA Aptamers
DNA bio-computing is an emerging trend in modern science that is based on interactions among biomolecules. Special types of DNAs are aptamers that are capable of selectively forming complexes with target compounds. This review is devoted to a discussion of logic gates based on aptamers for the purpo...
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MDPI AG,
2020-11-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_97f7a9b9133f4a19a3216c996ad7ab3f | ||
042 | |a dc | ||
100 | 1 | 0 | |a Mariia Andrianova |e author |
700 | 1 | 0 | |a Alexander Kuznetsov |e author |
245 | 0 | 0 | |a Logic Gates Based on DNA Aptamers |
260 | |b MDPI AG, |c 2020-11-01T00:00:00Z. | ||
500 | |a 10.3390/ph13110417 | ||
500 | |a 1424-8247 | ||
520 | |a DNA bio-computing is an emerging trend in modern science that is based on interactions among biomolecules. Special types of DNAs are aptamers that are capable of selectively forming complexes with target compounds. This review is devoted to a discussion of logic gates based on aptamers for the purposes of medicine and analytical chemistry. The review considers different approaches to the creation of logic gates and identifies the general algorithms of their creation, as well as describes the methods of obtaining an output signal which can be divided into optical and electrochemical. Aptameric logic gates based on DNA origami and DNA nanorobots are also shown. The information presented in this article can be useful when creating new logic gates using existing aptamers and aptamers that will be selected in the future. | ||
546 | |a EN | ||
690 | |a aptamer | ||
690 | |a logic gate | ||
690 | |a sensor | ||
690 | |a biosensor | ||
690 | |a Medicine | ||
690 | |a R | ||
690 | |a Pharmacy and materia medica | ||
690 | |a RS1-441 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Pharmaceuticals, Vol 13, Iss 11, p 417 (2020) | |
787 | 0 | |n https://www.mdpi.com/1424-8247/13/11/417 | |
787 | 0 | |n https://doaj.org/toc/1424-8247 | |
856 | 4 | 1 | |u https://doaj.org/article/97f7a9b9133f4a19a3216c996ad7ab3f |z Connect to this object online. |