Calcific Aortic Valve Disease-Natural History and Future Therapeutic Strategies

• Main Authors: Brunilda Alushi (Author), Lavinia Curini (Author), Mary Roxana Christopher (Author), Herko Grubitzch (Author), Ulf Landmesser (Author), Amedeo Amedei (Author), Alexander Lauten (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Calcific aortic valve disease (CAVD) is the most frequent heart valve disorder. It is characterized by an active remodeling process accompanied with valve mineralization, that results in a progressive aortic valve narrowing, significant restriction of the valvular area, and impairment of blood flow....