The <i>in vitro</i> neuroprotective activity of analogues of N-terminus substituted glyprolines

• Váldodahkkit: S. V. Nikolaev (Dahkki), I. O. Logvinov (Dahkki), K. N. Koliasnikova (Dahkki), E. A. Kuznetsova (Dahkki), P. I. Antipov (Dahkki), T. A. Antipova (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: LLC "Publisher OKI", 2020-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

In this work investigated the neuroprotective activity of analogues of substituted glyproline GZK-111 at the N-terminus in vitro. Oxidative stress caused by H2O2 (1.5 mM) led to significant decrease in the hippocampal cells HT-22 viability. The ethyl ester N-phenypropionyl-glycyl-proline (GZK-45) wa...