An In Vitro Platform to Study Reversible Endothelial-to-Mesenchymal Transition

• Main Authors: Muthu Kumar Krishnamoorthi (Author), Rajarajan A. Thandavarayan (Author), Keith A. Youker (Author), Arvind Bhimaraj (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endothelial cells can acquire a mesenchymal phenotype in response to external stimuli through both mechanical and biological factors, using a process known as endothelial-to-mesenchymal (EndoMT) transition. EndoMT is characterized by the decrease in endothelial characteristics, increase in mesenchym...