Isoforskolin Alleviates AECOPD by Improving Pulmonary Function and Attenuating Inflammation Which Involves Downregulation of Th17/IL-17A and NF-κB/NLRP3

• Main Authors: Chuang Xiao (Author), Sha Cheng (Author), Runfeng Li (Author), Yutao Wang (Author), Deyou Zeng (Author), Haiming Jiang (Author), Yaping Liang (Author), Rong Huang (Author), Hanxiao Pan (Author), Xiao Wu (Author), Yan Fang (Author), Chen Chen (Author), Xian Li (Author), Rongping Zhang (Author), Xinhua Wang (Author), Zifeng Yang (Author), Weimin Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic obstructive pulmonary disease (COPD), a major cause of morbidity and mortality worldwide, is widely considered to be related to cigarette smoke (CS), and viral infections trigger acute exacerbation of COPD (AECOPD). Isoforskolin (ISOF) is a bioactive component from the plant Coleus forskohli...