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DNAJB6 isoform specific knockdown: Therapeutic potential for limb girdle muscular dystrophy D1

Dominant missense mutations in DNAJB6, a co-chaperone of HSP70, cause limb girdle muscular dystrophy (LGMD) D1. No treatments are currently available. Two isoforms exist, DNAJB6a and DNAJB6b, each with distinct localizations in muscle. Mutations reside in both isoforms, yet evidence suggests that DN...

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Main Authors: Andrew R. Findlay (Author), May M. Paing (Author), Jil A. Daw (Author), Meade Haller (Author), Rocio Bengoechea (Author), Sara K. Pittman (Author), Shan Li (Author), Feng Wang (Author), Timothy M. Miller (Author), Heather L. True (Author), Tsui-Fen Chou (Author), Conrad C. Weihl (Author)
Format: Book
Published: Elsevier, 2023-06-01T00:00:00Z.
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