Transdermal iontophoresis delivery system for terazosin hydrochloride: an in vitro and in vivo study

• Main Authors: Changzhao Jiang (Author), Xiumei Jiang (Author), Xiumin Wang (Author), Jiaxu Shen (Author), Mengjie Zhang (Author), Leilei Jiang (Author), Rui Ma (Author), Tingting Gan (Author), Yingbiao Gong (Author), Jincui Ye (Author), Wenyan Gao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to construct a transdermal iontophoresis delivery system for terazosin hydrochloride (IDDS-TEH), which included a positive and negative electrode hydrogel prescription. Intact guinea pig skin was used as a model for the skin barrier function, and the current intensity, terazosin hyd...