Antimicrobial efficacy of synthetic and natural-derived novel endodontic irrigating solution - An In vitro study

Aim and Objective: This in vitro study was designed to comparatively evaluate the antimicrobial efficacy of peracetic acid (PAA - 0.5% and 1%), phytic acid (IP6 - 0.5% and 1%), and sodium hypochlorite (NaOCl - 3% and 5.25%) as irrigating agents against Enterococcus faecalis. Materials and Methods: A...

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Main Authors: Thangi Sowjanya (Author), Sudhakar Naidu (Author), Mahendra Varma Nadimpalli (Author), Gowtam Dev Dondapati (Author), T B V G Raju (Author), Parvathaneni Krishna Prasad (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2020-01-01T00:00:00Z.
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Summary:Aim and Objective: This in vitro study was designed to comparatively evaluate the antimicrobial efficacy of peracetic acid (PAA - 0.5% and 1%), phytic acid (IP6 - 0.5% and 1%), and sodium hypochlorite (NaOCl - 3% and 5.25%) as irrigating agents against Enterococcus faecalis. Materials and Methods: Agar plates were prepared using Mueller-Hinton (MH) agar. E. faecalis injected in nutrient broth at 37°C. Well diffusion methods were used to derive results. Plates were inoculated for 36 h at 37°C, and microbial zones of inhibition were recorded. Statistical analysis was performed with repeated measures of analysis of variance. Results: PAA (1%) and IP6 (1%) showed larger zones of microbial inhibition. PAA (0.5%) was statistically significant (P < 0.05) when compared to NaOCl (3% and 5.25%). Conclusion: PAA (1%) was used as an irrigating agent in endodontic failure cases.
Item Description:2231-0754
10.4103/jicdro.jicdro_44_19