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Ranirestat (AS-3201), a Potent Aldose Reductase Inhibitor, Reduces Sorbitol Levels and Improves Motor Nerve Conduction Velocity in Streptozotocin-Diabetic Rats

Ranirestat (AS-3201) is a novel aldose reductase (AR) inhibitor with potentially beneficial effects on diabetic sensorimotor polyneuropathy. In this study, we performed a kinetic analysis to determine the mode of inhibition of ranirestat on AR and investigated the effects of ranirestat on sorbitol l...

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Bibliographic Details
Main Authors:	Takafumi Matsumoto (Author), Yoshiyuki Ono (Author), Masuo Kurono (Author), Akemi Kuromiya (Author), Keiji Nakamura (Author), Vera Bril (Author)
Format:	Book
Published:	Elsevier, 2008-01-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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