AG490, a JAK2-specific inhibitor, downregulates the expression and activity of organic anion transporter-3
Human organic anion transporter-3 (hOAT3) is richly expressed in the kidney, where it plays critical roles in the secretion of clinically important drugs, including anti-viral therapeutics, anti-cancer drugs, antibiotics, antihypertensives, and anti-inflammatories. In the current study, we examined...
Saved in:
Main Authors: | Jinghui Zhang (Author), Chenchang Liu (Author), Guofeng You (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2018-03-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The activity of organic anion transporter-3: Role of dexamethasone
by: Haoxun Wang, et al.
Published: (2018) -
Chloroquine and Hydroxychloroquine, as Proteasome Inhibitors, Upregulate the Expression and Activity of Organic Anion Transporter 3
by: Zhengxuan Liang, et al.
Published: (2023) -
Topotecan and Ginkgolic Acid Inhibit the Expression and Transport Activity of Human Organic Anion Transporter 3 by Suppressing SUMOylation of the Transporter
by: Zhou Yu, et al.
Published: (2024) -
Insulin-like growth factor 1 modulates the phosphorylation, expression, and activity of organic anion transporter 3 through protein kinase A signaling pathway
by: Jinghui Zhang, et al.
Published: (2020) -
Recent Advances on the Regulations of Organic Anion Transporters
by: Zhou Yu, et al.
Published: (2024)