Adenosine Receptor Stimulation Improves Glucocorticoid-Induced Osteoporosis in a Rat Model

• Main Authors: Gabriele Pizzino (Author), Natasha Irrera (Author), Federica Galfo (Author), Giacomo Oteri (Author), Marco Atteritano (Author), Giovanni Pallio (Author), Federica Mannino (Author), Angelica D'Amore (Author), Enrica Pellegrino (Author), Federica Aliquò (Author), Giuseppe P. Anastasi (Author), Giuseppina Cutroneo (Author), Francesco Squadrito (Author), Domenica Altavilla (Author), Alessandra Bitto (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glucocorticoid-induced osteoporosis (GIO) is a secondary cause of bone loss. Bisphosphonates approved for GIO, might induce jaw osteonecrosis; thus additional therapeutics are required. Adenosine receptor agonists are positive regulators of bone remodeling, thus the efficacy of adenosine receptor st...