Voltage- and temperature-dependent allosteric modulation of alpha7 nicotinic receptors by PNU120596

• Autores principales: Fabrio eSitzia (Autor), Jon T Brown (Autor), Andrew eRandall (Autor), John eDunlop (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2011-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Alpha7 nicotinic receptors (a7nAChR) are widely distributed throughout the central nervous system (CNS) and are found at particularly high levels in the hippocampus and cortex. Several lines of evidence indicate that pharmacological enhancement of a7nAChRs function could be a potential therapeutic r...