Cover Image

Actoprotective activity of 5-(2-bromophenyl)-4-amino-4H-1,2,4-triazole-3-thione and its S-derivatives

Aim. The paper shows the actoprotective (anti-fatigue), activity of 1,2,4-triazole derivatives. Methods and results. The analysis of action was conducted for the synthesized 2-(5-(2-bromphenyl)-4-amino-4H-1,2,4-triazol-3-ylthio) acetic acid salts. We have revealed some patterns regarding to the chem...

Full description

Saved in:

Bibliographic Details
Main Author:	Ye. S. Pruglo (Author)
Format:	Book
Published:	Zaporozhye State Medical University, 2016-04-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Synthesis of novel 3-(2-bromophenyl)-4-substituted-1H-1,2,4-triazole-5(4H)-thiones derivatives
by: A. A. Safonov, et al.
Published: (2020)

Actoprotective activity research of 2-((5-(2-bromophenyl)-4-substituted-4H-1,2,4-triazole-3-yl)thio)acetates
by: A. A. Safonov, et al.
Published: (2020)

Analgesic activity of 4-amino-5-methyl-4H-1,2,4-triazol-3-thiones
by: T. V. Kravchenko, et al.
Published: (2018)

Diuretic activity of 3-(5-bromfuran-2-yl)-4-r-(4h)-1,2,4-triazole-5-thione, their S-derivatives and 2-(5-bromfuran-2-yl)-5-r'-thiazolo[3,2-b][1,2,4]triazole-6(5h)-ones
by: Ye. S. Pruglo, et al.
Published: (2015)

ACUTE TOXICITYOF 4-AMINO-5-(2-, 3-, 4-NITROPHENYL)-1,2,4-TRIAZOLE-3-THIONES AND ITS DERIVATIVES
by: М. O. Shcherbak, et al.
Published: (2014)

Antidepressant activity of 4-amino-5-(alkyl-, aryl-, heteryl)-1,2,4-triazole-3-thione benzylidene derivatives
by: Ye. S. Pruhlo
Published: (2018)

Some transformations in a series of 4-amino-1,2,4-triazole-3-thion derivatives
by: O. A. Bihdan, et al.
Published: (2024)

DFT-analysis of protolytic equivalents of 5-(aryl)-4-(methyl,amino)-1,2,4-triazole-3(2H)-thione
by: O. A. Bihdan, et al.
Published: (2022)

The research of acute toxicity of 4-amino-5-(4-(tert-butyl)phenyl)-4H-1,2,4-triazoles-3-thiol derivatives
by: I. I. Аksyonova-Seliuk, et al.
Published: (2017)

In silico study of new bis-3R, 4R'-5-(((1H-1,2,4-triazole-5-yl)thio)methyl)-4H-1,2,4-triazole-3-thione derivatives
by: Ye. O. Karpun, et al.
Published: (2019)

Synthesis and structure of some new Schiff bases, derivatives of 2-((4-((R-benzylidene)amino)-5-(2-fluorophenyl)-4H-1,2,4-triazole-3-yl)thio)acetohydrazides
by: Ye. S. Pruglo
Published: (2018)

Synthesis and research of the physical-chemical properties of 5-((2-bromphenyl)-4-amino-4H-1,2,4-triazole-3-ylthio)acetic acid salts
by: Ye. S. Pruglo
Published: (2018)

Antioxidant activity of salts of 2-(5-R-4-amino-1,2,4-triazole-3-ylthio)acetic acid
by: Ye. S. Pruglo
Published: (2017)

Antifatigue action of the 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thione alkyl derivatives
by: D. M. Danilchenko, et al.
Published: (2018)

Synthesis, antimicrobial and antifungal activity of 3-(2-bromophenyl)-5-(alkylthio)-4-phenyl-4H-1,2,4-triazoles
by: A. A. Safonov, et al.
Published: (2022)

Synthesis and structure of new 4-amino-5-(2-R1-phenyl)-1,2,4-triazole-3-thiol alkilderivatives
by: Ye. S. Pruglo
Published: (2017)

Effect of 4-benzylidenamino-5-phenyl-4Н-1,2,4-triazole-3-thiones and salts of 2-(4-amino-5-phenyl-4Н-1,2,4-triazole-3-ylthio)acetic acid on central component of nociceptive system
by: Ye. S. Pruhlo
Published: (2016)

The study of analgesic effect of 5-(furan-2-yl, 2-methylfuran-3-yl)-4-amino-1,2,4-triazole-3-thion derivatives
by: D. M. Danilchenko
Published: (2018)

Synthesis and properties of 5-(((5-amino-1,3,4-thiadiazole-2-yl)thio)methyl)-4-phenyl-1,2,4-triazole-3-thione and its some S-derivatives
by: A. S. Hotsulia, et al.
Published: (2020)

A study of actoprotective activity of new 3-(thiophen-2-ylmethyl)-1H-1,2,4-triazole-5-thiol derivatives
by: A. A. Safonov
Published: (2020)

Actoprotective activity of some 5-(thiophen-3-ylmethyl)-4-R1-1,2,4-triazole-3-thiols derivatives
by: O. A. Bihdan
Published: (2020)

A study of antimicrobial and antifungal activity of 2-((5-(2-bromophenyl)-4-substituted-4H-1,2,4-triazol-3-yl)thio)acetates
by: A. A. Safonov, et al.
Published: (2020)

Synthesis methods of 1,2,4-triazole-3-thiones: review
by: Yu. S. Frolova, et al.
Published: (2024)

The acute toxicity of 5-thio-substituted 3-(5-bromofuran-2-yl)-4-ethyl-(4H)-1,2,4-triazole derivatives
by: E. S. Pruglo, et al.
Published: (2015)

Synthesis of ylidene derivatives of 4-amino-5-(4-tert-butylphenyl)-4H-1,2,4-triazole-3-thiol
by: I. I. Aksionova, et al.
Published: (2015)

Hepatoprotective activity of 1,2,4-triazole-3-thione derivatives, which contains on c5-atomic carbon hydroxy(phenyl)methyl dependent
by: A. M. Rud, et al.
Published: (2018)

Establishment of diuretic activity indicators for (3-thio-4-R-4-H-1,2,4-triazole-5-yl)(phenyl)methanols and their derivatives
by: A. M. Rud, et al.
Published: (2018)

Antiradical activity of novel 4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol derivatives
by: A. A. Safonov, et al.
Published: (2021)

Acute toxicity of 5-(2-, 3-, 4-methoxyphenyl, (3,4,5-trimethoxyphenyl)-)-1,2,4-triazole-3-thiones and its thioderivatives
by: Yu. G. Samelyuk, et al.
Published: (2015)

Synthesis and physicochemical properties 4-((R))amino)-5-methyl-4H-1,2,4-triazole-3-thiols
by: T. V. Kravchenko, et al.
Published: (2018)

Discussion of antimicrobial and antifungal activity of 4-amino-5-methyl-4H-1,2,4-triazole-3-thiol
by: T. V. Kravchenko, et al.
Published: (2017)

Search of potential antidiabetic drugs in range of 5-(phenoxymethylene)-4-R-1,2,4-triazole-3-thions
by: Yu. M. Kucheryavyi
Published: (2016)

Acute toxicity of S-derivatives of 4-R-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazoles
by: O. A. Suhak, et al.
Published: (2017)

4-Amino-1,2,4-triazole-3-thione as a Promising Scaffold for the Inhibition of Serine and Metallo-<i>β</i>-Lactamases
by: Pasquale Linciano, et al.
Published: (2020)

Chemical properties of amino- and thio-derivatives of 1,2,4-triazoles
by: A. G. Kaplaushenko
Published: (2015)

Synthesis and properties of some S-derivatives of 4-phenyl-5-((5-phenylamino-1,3,4-thiadiazole-2-ylthio)methyl)-1,2,4-triazole-3-thione
by: A. S. Hotsulia, et al.
Published: (2019)

Acute toxicity and "structure-action" dependence of 4-(R-benzylidenamino)-5-methyl-4H-1,2,4-triazoles 3-tion
by: T. V. Kravchenko, et al.
Published: (2017)

Investigation of diuretic activity of 4-R-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazoles' derivatives
by: O. A. Suhak, et al.
Published: (2018)

Antimicrobial and antifungal activity of new 4-(5-((5-(alkylthio)-4-R-4H-1,2,4-triazole-3-yl)thio)-1H-1,2,4-triazole-3-yl)pyridines
by: Ye. O. Karpun, et al.
Published: (2020)

Anti-inflammatory activity of 2-(5-((theophylline-7'-yl)methyl)-4-R-4H-1,2,4-triazole-3-ylthio)acetic acid salts
by: A. S. Gotsulya, et al.
Published: (2014)