Structural biology of HER2/ERBB2 dimerization: mechanistic insights and differential roles in healthy versus cancerous cells

• Главные авторы: Jayasree Santhanakrishnan (Автор), Prabhu Meganathan (Автор), Hemamalini Vedagiri (Автор)
• Формат: ‌
• Опубликовано: Open Exploration Publishing Inc., 2024-07-01T00:00:00Z.
• Предметы: article
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Aim: Present study was done to understand the dimerization of HER2/ERBB2 in normal and cancer cells using in-silico study. Methods: Pathway analysis was done using Reactome. Structure of HER2/ERBB2 protein was obtained from PDB database, and using Schrödinger software protein structure was analysed...