Association Between NR3C1 Mutations and Glucocorticoid Resistance in Children With Acute Lymphoblastic Leukemia

• Main Authors: Haiyan Liu (Author), Ziping Li (Author), Fei Qiu (Author), Chunjie Li (Author), Xiaojing Lin (Author), Yingyi He (Author), Maoxiang Qian (Author), Yuanbin Song (Author), Hui Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Treatment outcomes in children with acute lymphoblastic leukemia (ALL) have been improved substantially, with a cure rate exceeding 80% using conventional therapy. However, the outcome for patients with relapsed/refractory ALL remains unsatisfactory, despite the fact that these patients generally re...