Overexpression of miR-21-5p promotes proliferation and invasion of colon adenocarcinoma cells through targeting CHL1

• Главные авторы: Weihua Yu (Автор), Kongxi Zhu (Автор), Yulong Wang (Автор), Hualong Yu (Автор), Jianqiang Guo (Автор)
• Формат: ‌
• Опубликовано: BMC, 2018-07-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract Background This study aims to investigate the effect of miR-21-5p on process of colon adenocarcinoma (COAD) cells and its connection with neural cell adhesion molecule L1 (CHL1). Methods Different expressions of mRNAs and miRNAs were calculated with microarray analysis. QRT-PCR and western...