Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case
Lithium is among the mainstays of treatment for bipolar disorder. Bariatric surgery can considerably change the oral bioavailability of drugs, particularly lithium. In this review, a 36-year-old male patient is described, who presented with lithium toxicity, including neurologic and gastric symptoms...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
American Association of Psychiatric Pharmacists,
2022-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Lithium is among the mainstays of treatment for bipolar disorder. Bariatric surgery can considerably change the oral bioavailability of drugs, particularly lithium. In this review, a 36-year-old male patient is described, who presented with lithium toxicity, including neurologic and gastric symptoms after undergoing Roux-en-Y gastric bypass. The mechanism of lithium toxicity is discussed; recommendations for clinicians regarding lithium use in postsurgical patients are provided; and previous case reports of lithium toxicity post-gastric bypass surgery are analyzed. Awareness and education of lithium absorption changes postbariatric surgery is essential for optimal patient care. Close clinical and drug concentration level monitoring is warranted. |
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| Item Description: | 2168-9709 10.9740/mhc.2022.06.214 |