Cover Image

Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway

The purpose of this study is to investigate the protective effect of kaempferol (KAE), the main active monomer from Penthorum chinense Pursh, on hepatic ischemia/reperfusion injury (HI/RI) and its specific mechanism. HI/RI is a common complication closely related to the prognosis of liver surgery, a...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yifan Chen (Author), Tongxi Li (Author), Peng Tan (Author), Hao Shi (Author), Yonglang Cheng (Author), Tianying Cai (Author), Junjie Bai (Author), Yichao Du (Author), Wenguang Fu (Author)
Format:	Book
Published:	Frontiers Media S.A., 2022-04-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Regulation of intestinal microflora and metabolites of Penthorum chinense Pursh on alcoholic liver disease
by: Hui Zhang, et al.
Published: (2024)

Characterization of the anti-Staphylococcus aureus fraction from Penthorum chinense Pursh stems
by: Bin Ding, et al.
Published: (2019)

Hepatoprotective properties of Penthorum chinense Pursh against carbon tetrachloride-induced acute liver injury in mice
by: Meng Wang, et al.
Published: (2017)

Penthorum chinense Pursh improves type 2 diabetes mellitus via modulating gut microbiota in db/db mice
by: Jilei Hu, et al.
Published: (2023)

Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulation of liver metabolism
by: Sujuan Wang, et al.
Published: (2023)

Integrated Chemical Interpretation and Network Pharmacology Analysis to Reveal the Anti-Liver Fibrosis Effect of Penthorum chinense
by: Zenan Du, et al.
Published: (2022)

Corrigendum: Integrated chemical interpretation and network pharmacology analysis to reveal the anti-liver fibrosis effect of Penthorum chinense
by: Zenan Du, et al.
Published: (2022)

Bardoxolone Methyl Ameliorates Myocardial Ischemia/Reperfusion Injury by Activating the Nrf2/HO-1 Signaling Pathway
by: Anwu Huang, et al.
Published: (2023)

The Nrf2/HO-1 Pathway Mediates the Antagonist Effect of L-Arginine On Renal Ischemia/Reperfusion Injury in Rats
by: Fei Tong, et al.
Published: (2017)

Glycolysis-Related LINC02432/Hsa-miR-98-5p/HK2 Axis Inhibits Ferroptosis and Predicts Immune Infiltration, Tumor Mutation Burden, and Drug Sensitivity in Pancreatic Adenocarcinoma
by: Peng Tan, et al.
Published: (2022)

Methane saline suppresses ferroptosis via the Nrf2/HO-1 signaling pathway to ameliorate intestinal ischemia-reperfusion injury
by: Qingrui Fan, et al.
Published: (2024)

Samarcandin protects against testicular ischemia/reperfusion injury in rats via activation of Nrf2/HO-1-mediated antioxidant responses
by: Maged S. Abdel-Kader, et al.
Published: (2023)

Kaempferol Protects Against Cerebral Ischemia Reperfusion Injury Through Intervening Oxidative and Inflammatory Stress Induced Apoptosis
by: Jing Wang, et al.
Published: (2020)

Kaempferol Alleviates Oxidative Stress and Apoptosis Through Mitochondria-dependent Pathway During Lung Ischemia-Reperfusion Injury
by: Chunli Yang, et al.
Published: (2021)

Kaempferol Protects Blood Vessels From Damage Induced by Oxidative Stress and Inflammation in Association With the Nrf2/HO-1 Signaling Pathway
by: He Yao, et al.
Published: (2020)

Activation of Nrf2/HO-1 Pathway by Glycogen Synthase Kinase-3β Inhibition Attenuates Renal Ischemia/Reperfusion Injury in Diabetic Rats
by: Xiaohua Shen, et al.
Published: (2017)

Paeonol Attenuates Hepatic Ischemia/Reperfusion Injury by Modulating the Nrf2/HO-1 and TLR4/MYD88/NF-κB Signaling Pathways
by: Mohamed A. Morsy, et al.
Published: (2022)

Renal Ischemia/Reperfusion Mitigation via Geraniol: The Role of Nrf-2/HO-1/NQO-1 and TLR2,4/MYD88/NFκB Pathway
by: Maged E. Mohamed, et al.
Published: (2022)

Kaempferol Improves Lung Ischemia-Reperfusion Injury via Antiinflammation and Antioxidative Stress Regulated by SIRT1/HMGB1/NF-κB Axis
by: Chunli Yang, et al.
Published: (2020)

Sappanone A Protects Against Myocardial Ischemia Reperfusion Injury by Modulation of Nrf2
by: Shi X, et al.
Published: (2020)

Isoliquiritigenin Ameliorates Ischemia-Induced Myocardial Injury via Modulating the Nrf2/HO-1 Pathway in Mice
by: Yao D, et al.
Published: (2022)

HO-1 Upregulation by Kaempferol via ROS-Dependent Nrf2-ARE Cascade Attenuates Lipopolysaccharide-Mediated Intercellular Cell Adhesion Molecule-1 Expression in Human Pulmonary Alveolar Epithelial Cells
by: Chien-Chung Yang, et al.
Published: (2022)

Rutaecarpine may improve neuronal injury, inhibits apoptosis, inflammation and oxidative stress by regulating the expression of ERK1/2 and Nrf2/HO-1 pathway in rats with cerebral ischemia-reperfusion injury
by: Han M, et al.
Published: (2019)

Dexmedetomidine postconditioning attenuates myocardial ischemia/reperfusion injury by activating the Nrf2/Sirt3/SOD2 signaling pathway in the rats
by: Bin Hu, et al.
Published: (2023)

Acacetin alleviates myocardial ischaemia/reperfusion injury by inhibiting oxidative stress and apoptosis via the Nrf-2/HO-1 pathway
by: Chan Wu, et al.
Published: (2022)

Ginsenoside Rg3 attenuates myocardial ischemia/reperfusion-induced ferroptosis via the keap1/Nrf2/GPX4 signaling pathway
by: GuoFu Zhong, et al.
Published: (2024)

Pharmacological Protection against Ischemia-Reperfusion Injury by Regulating the Nrf2-Keap1-ARE Signaling Pathway
by: Bercis Imge Ucar, et al.
Published: (2021)

Oleanolic Acid Alleviates Cerebral Ischemia/Reperfusion Injury via Regulation of the GSK-3β/HO-1 Signaling Pathway
by: Kaili Lin, et al.
Published: (2021)

Ezetimibe Prevents Ischemia/Reperfusion-Induced Oxidative Stress and Up-Regulates Nrf2/ARE and UPR Signaling Pathways
by: Denise Peserico, et al.
Published: (2020)

Dietary Inorganic Nitrate Protects Hepatic Ischemia-Reperfusion Injury Through NRF2-Mediated Antioxidative Stress
by: Shaorong Li, et al.
Published: (2021)

Andrade-Oliveira Salvianolic Acid B Modulates Caspase-1-Mediated Pyroptosis in Renal Ischemia-Reperfusion Injury via Nrf2 Pathway
by: Yu Pang, et al.
Published: (2020)

The relationship of redox signaling with the risk for atherosclerosis
by: Sujuan Lei, et al.
Published: (2024)

Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway
by: Zhuo Feng, et al.
Published: (2021)

Diallyl Trisulfide Protects Rat Brain Tissue against the Damage Induced by Ischemia-Reperfusion through the Nrf2 Pathway
by: Carlos A. Silva-Islas, et al.
Published: (2019)

Protective Effect of Pravastatin on Myocardial Ischemia Reperfusion Injury by Regulation of the miR-93/Nrf2/ARE Signal Pathway
by: Liu Z, et al.
Published: (2020)

Gerontoxanthone I and Macluraxanthone Induce Mitophagy and Attenuate Ischemia/Reperfusion Injury
by: Qian Xiang, et al.
Published: (2020)

Chloroplast genome of Thesium chinense: The insight into phylogeny of Santalaceae
by: Zhenyu Zhao, et al.
Published: (2023)

Benzoylaconine Protects Skeletal Muscle Against Ischemia-Reperfusion Injury Through Activation of IF1-Dependent AMPK/Nrf2 Axis
by: Cui Y, et al.
Published: (2024)

Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway
by: Liu D, et al.
Published: (2020)

Possible Implication of Nrf2, PPAR-γ and MAPKs Signaling in the Protective Role of Mangiferin against Renal Ischemia/Reperfusion in Rats
by: Abdallah M. Gendy, et al.
Published: (2022)