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The importance of the enzyme Gamma-glutamyltransferase in the pathogenic cluster in type2 diabetic patient

Introduction. Gamma-glutamyltransferase (GGT) is a liver enzyme involved in inflammation and oxidative stress. It is already known that MCP-1 (Monocyte Chemoattractant Protein-1) and TNF-α (tumour necrosis factor) as inflammatory markers, ICAM-1 (Intercellular Adhesion Molecule-1) as an endothelial...

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Main Authors: Virgolici Bogdana (Author), Dobre Maria Zinaida (Author), Lixandru Daniela (Author), Petcu Laura (Author), Picu Ariana (Author), Ionescu-Târgovişte Constantin (Author), Greabu Maria (Author), Bacanu Elena Violeta (Author)
Format: Book
Published: Sciendo, 2024-06-01T00:00:00Z.
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Summary:Introduction. Gamma-glutamyltransferase (GGT) is a liver enzyme involved in inflammation and oxidative stress. It is already known that MCP-1 (Monocyte Chemoattractant Protein-1) and TNF-α (tumour necrosis factor) as inflammatory markers, ICAM-1 (Intercellular Adhesion Molecule-1) as an endothelial dysfunctional marker, and glutathione, as an antioxidant, have abnormal levels in type 2 diabetic patients. The aim of this study was to evaluate the specific biological picture of type 2 diabetic patients that also associate higher GGT activity.
Item Description:2501-062X
10.2478/rjim-2024-0006

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