Cover Image

Traditional Chinese Medicine JianPiHuaTan formula improving quality of life and survival in patients with colorectal cancer through RAS/RAF downstream signaling pathways

ObjectiveJianPiHuaTan Formula (JPHTF), a traditional Chinese medicine (TCM), has been utilized as an adjunctive therapy for colorectal cancer (CRC). The study aims to evaluate the potential clinical benefits of JPHTF and its effectiveness in inhibiting tumor growth.Methods300 stage II/III CRC patien...

Full description

Saved in:

Bibliographic Details
Main Authors:	Jian He (Author), Guojun Li (Author), Yu Wu (Author), Tong Zhang (Author), Mingjiang Yao (Author), Mingxuan Zang (Author), Jianhua Zou (Author), Jinjie Song (Author), Liusheng Li (Author), Qian Chen (Author), Guang Cao (Author), Linlin Cai (Author)
Format:	Book
Published:	Frontiers Media S.A., 2024-06-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Targeting RAF dimers in RAS mutant tumors: From biology to clinic
by: Huanhuan Yin, et al.
Published: (2024)

RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy
by: Ichiro Yajima, et al.
Published: (2012)

Explore the active ingredients and potential mechanisms of JianPi QingRe HuaYu Methods in the treatment of gastric inflammation-cancer transformation by network pharmacology and experimental validation
by: Kechao Nie, et al.
Published: (2023)

Oridonin-Induced A431 Cell Apoptosis Partially Through Blockage of the Ras/Raf/ERK Signal Pathway
by: Dan Li, et al.
Published: (2007)

Design, Synthesis, and Antileukemic Evaluation of a Novel Mikanolide Derivative Through the Ras/Raf/MEK/ERK Pathway
by: Qing Rao, et al.
Published: (2022)

High-Pressure Supercritical CO2 Extracts of Ganoderma lucidum Fruiting Body and Their Anti-hepatoma Effect Associated With the Ras/Raf/MEK/ERK Signaling Pathway
by: Liping Zhu, et al.
Published: (2020)

Jian Yun Qing Hua Decoction inhibits malignant behaviors of gastric carcinoma cells via COL12A1 mediated ferroptosis signal pathway
by: Baoxinzi Liu, et al.
Published: (2023)

Effects of Jian Pi Qing Chang Hua Shi decoction on mucosal injuries in a 2,4,6-trinitrobenzene sulphonic acid-induced inflammatory bowel disease rat model
by: Huicun Zhang, et al.
Published: (2021)

A personalized molecular approach in multiple myeloma: the possible use of RAF/RAS/MEK/ERK and BCL-2 inhibitors
by: Vincenzo Raimondi, et al.
Published: (2022)

Network Pharmacology and Experimental Validation to Explore the Mechanism of Qing-Jin-Hua-Tan-Decoction Against Acute Lung Injury
by: Shunli Xiao, et al.
Published: (2022)

Hua-Tan-Sheng-Jing Decoction Treats Obesity With Oligoasthenozoospermia by Up-Regulating the PI3K-AKT and Down-Regulating the JNK MAPK Signaling Pathways: At the Crossroad of Obesity and Oligoasthenozoospermia
by: Yang Dong, et al.
Published: (2022)

JianPi-QingHua formula attenuates nonalcoholic fatty liver disease by regulating the AMPK/SIRT1/NF-κB pathway in high-fat-diet-fed C57BL/6 mice
by: Jing Tian, et al.
Published: (2023)

Salvianolic Acid Alleviated Blood–Brain Barrier Permeability in Spontaneously Hypertensive Rats by Inhibiting Apoptosis in Pericytes via P53 and the Ras/Raf/MEK/ERK Pathway
by: Wu Q, et al.
Published: (2020)

Downstream
by: Siwertz, Sigfrid, 1882-1970; Classen, E. (Ernest), 1881- [Translator]

GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways
by: Jiang Pi, et al.
Published: (2017)

Dave Dawson with the R.A.F.
by: Bowen, Robert Sidney, 1900-1977

Jian-Pi-Bu-Xue-Formula Alleviates Cyclophosphamide-Induced Myelosuppression via Up-Regulating NRF2/HO1/NQO1 Signaling
by: Qiuju Huang, et al.
Published: (2020)

Jian-Pi-Yi-Shen Formula ameliorates chronic kidney disease: involvement of mitochondrial quality control network
by: Xinhui Liu, et al.
Published: (2018)

The Art of Chinese Swordsmanship: A Manual of Taiji Jian
by: Noah Nunberg
Published: (2012)

The Art of Chinese Swordsmanship: A Manual of Taiji Jian
by: Noah Nunberg
Published: (2012)

The Art of Chinese Swordsmanship: A Manual of Taiji Jian
by: Noah Nunberg
Published: (2012)

Network Pharmacology and Experimental Verification Strategies to Illustrate the Mechanism of Jian-Pi-Yi-Shen Formula in Suppressing Epithelial-Mesenchymal Transition
by: Yuan Zhao, et al.
Published: (2022)

A Yankee Flier with the R.A.F.
by: Montgomery, Rutherford G. (Rutherford George), 1896-1985; Laune, Paul, 1899-1977 [Illustrator]

Raf-mediated cardiac hypertrophy in adult Drosophila
by: Lin Yu, et al.
Published: (2013)

A Chinese herbal decoction, Jian-Pi-Yi-Shen, regulates the expressions of erythropoietin and pro-inflammatory cytokines in cultured cells
by: Jianping Chen, et al.
Published: (2018)

The effect of Jian Gan powder on the proliferation, migration and polarization of macrophages and relative mechanism
by: Kun Li, et al.
Published: (2024)

First person - Jiang-Hua Liu
Published: (2020)

Broad Anti-Viral Capacities of Lian-Hua-Qing-Wen Capsule and Jin-Hua-Qing-Gan Granule and Rational use Against COVID-19 Based on Literature Mining
by: Mingfei Shi, et al.
Published: (2021)

Experiments : tan senzills i tan exemplificadors
by: M. Carme Gilart Barranquero
Published: (2008)

JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway
by: Zhongtang Li, et al.
Published: (2024)

Rãs
by: Maria de Fátima Sousa e Silva
Published: (2014)

Comprehensive analysis to evaluate the molecular biological mechanism and clinical efficacy of Jian Pi Yang Zheng Xiao Zheng in the treatment of gastric cancer
by: Yuan-jie Liu, et al.
Published: (2024)

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors
by: Paweletz Cloud, et al.
Published: (2010)

Involvement of Circulating Exosomal MicroRNAs in Jian-Pi-Yi-Shen Formula Protection Against Adenine-Induced Chronic Kidney Disease
by: Xinhui Liu, et al.
Published: (2021)

Mechanism of TangGanJian on nonalcoholic fatty liver disease with type 2 diabetes mellitus
by: Yanbo Fan, et al.
Published: (2018)

Distinct Responses of Gut Microbiota to Jian-Pi-Yi-Shen Decoction Are Associated With Improved Clinical Outcomes in 5/6 Nephrectomized Rats
by: Lin Zheng, et al.
Published: (2020)

Winning His Wings: A Story of the R.A.F.
by: Westerman, Percy F. (Percy Francis), 1876-1959; Hodgson, E. S. (Edward Smith), 1866-1937 [Illustrator]

Anti-osteoporotic effects of Yi Mai Jian on bone metabolism of ovariectomized rats
by: Bin Shi, et al.
Published: (2024)

Jian-Pi-Yi-Shen Formula Improves Adenine-Induced Chronic Kidney Disease via Regulating Tryptophan Metabolism and Aryl Hydrocarbon Receptor Signaling
by: Xinhui Liu, et al.
Published: (2022)

Tibetan medicine Bang Jian: a comprehensive review on botanical characterization, traditional use, phytochemistry, and pharmacology
by: Yuan Li, et al.
Published: (2023)