Dactilitis and oligoarthritis after BCG immunotherapy in a patient affected by bladder cancer

The treatment of bladder cancer with Bacillus of Calmette-Guerin (BCG) immunotherapy can induce the appearance of a reactive disorder. The Authors describe a 55-year-old male patient with bladder cancer treated with endovesical instillation of BCG immunotherapy, followed after the fifth application...

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Main Authors: N. Elkhaldi (Author), L. Bernardini (Author), C.U. Manzini (Author), M.T. Mascia (Author), C. Ferri (Author)
Format: Book
Published: PAGEPress Publications, 2011-09-01T00:00:00Z.
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100 1 0 |a N. Elkhaldi  |e author 
700 1 0 |a L. Bernardini  |e author 
700 1 0 |a C.U. Manzini  |e author 
700 1 0 |a M.T. Mascia  |e author 
700 1 0 |a C. Ferri  |e author 
245 0 0 |a Dactilitis and oligoarthritis after BCG immunotherapy in a patient affected by bladder cancer 
260 |b PAGEPress Publications,   |c 2011-09-01T00:00:00Z. 
500 |a 10.4081/reumatismo.2006.230 
500 |a 0048-7449 
500 |a 2240-2683 
520 |a The treatment of bladder cancer with Bacillus of Calmette-Guerin (BCG) immunotherapy can induce the appearance of a reactive disorder. The Authors describe a 55-year-old male patient with bladder cancer treated with endovesical instillation of BCG immunotherapy, followed after the fifth application by asymmetric oligoarthritis and dactilitis. The observed positivity of both HLA-B27 and HLA-B51 antigens reinforces the hypothesis of a reactive form, possibly through "molecular mimicry" mechanism. The discontinuation of BCG instillation along which a therapeutic attempt with NSAD failed to improve the rheumatic manifestation, which completely remitted after a four-month course of oral steroids. No relapses of joint and tendon involvement was observed during the following five-month period. The clinico- pathogenetic implications suggested by this case are discussed. 
546 |a EN 
546 |a IT 
690 |a Medicine 
690 |a R 
690 |a Internal medicine 
690 |a RC31-1245 
655 7 |a article  |2 local 
786 0 |n Reumatismo, Vol 58, Iss 3, Pp 230-232 (2011) 
787 0 |n http://www.reumatismo.org/index.php/reuma/article/view/274 
787 0 |n https://doaj.org/toc/0048-7449 
787 0 |n https://doaj.org/toc/2240-2683 
856 4 1 |u https://doaj.org/article/9a88f47f2a724c068a1102d34353eedb  |z Connect to this object online.