Investigation of <i>N</i>-Acetyltransferase 2-Mediated Drug Interactions of Amifampridine: In Vitro and In Vivo Evidence of Drug Interactions with Acetaminophen

Amifampridine is a drug used for the treatment of Lambert-Eaton myasthenic syndrome (LEMS) and was approved by the Food and Drug Administration (FDA) of the United States (US) in 2018. It is mainly metabolized by <i>N</i>-acetyltransferase 2 (NAT2); however, investigations of NAT2-mediat...

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Main Authors: Yeo-Dim Park (Author), Yoon-Jee Chae (Author), Han-Joo Maeng (Author)
Format: Book
Published: MDPI AG, 2023-05-01T00:00:00Z.
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3rd Floor Main Library

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