Probes for the heterogeneity of muscimol binding sites in rat brain

• Main Authors: Veronika Müller (Author), Margot Ernst (Author), Aygul Baykuchkarova (Author), Filip Koniuszewski (Author), Konstantina Bampali (Author), Thomas Seidel (Author), Petra Scholze (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The plant-based alkaloid muscimol is a potent agonist of inhibitory GABAA-neurotransmitter receptors. GABAA receptors are a heterogeneous family of pentameric complexes, with 5 out of 19 subunits assembling around the central anion pore. Muscimol is considered to bind to all receptor s...