Potensi Antelmintik Ekstrak Etanol Daun Mangga Arumanis (Mangifera indica L.) pada Cacing Ascaridia galli dan Raillietina tetragona secara In Vitro

• Main Authors: Robiyanto Robiyanto (Author), Ria Kusuma (Author), Eka Kartika Untari (Author)
• Format: Book
• Published: Universitas Indonesia, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2407-2354; 2477-0612
• Keywords: anthelmintic; arumanis mango; Ascaridia galli; Raillietina tetragona; Pharmacy and materia medica; RS1-441; Therapeutics. Pharmacology; RM1-950
• Source: Pharmaceutical Sciences and Research, Vol 5, Iss 2, Pp 81-89 (2018)

Plants havepotential as a traditional medicine, one of them is arumanis mango (Mangifera indica L.) which is suspected have anthelmintic activity. The aim of this research is to know the anthelmintic activity of ethanol extract of arumanis mango leaves on Ascaridia galli worm and Raillietina tetragona in vitro, to know the effect of increasing extract concentration and to know LC50 and LT50 value from extract. The concentration of extract used were 5mg/ml, 25mg/ml and 50mg/ml, normal control (NaCl 0,9%) and positive control (mebendazole 5 mg/ml). The time and number of worm deaths were observed and analyzed using SPSS One Way Anova, Post hoc (LSD) and Probit. The results showed normal controls different significantly with all treatment groups. Concentrations of extracts 25mg/ml and 50mg/ml had time and number of worm deaths that didn't different significantly with mebendazole 5mg/ml p=0.466 and p=0.760 at Ascaridia galli, p=0.093 and p=0.566 on Raillietina tetragona, there is an effect of increasing the concentration of extract on the increase of anthelmintic activity. The value of LC50 extract on Ascaridia galli and Raillietina tetragona are: 2,6mg/ml and 3,1mg/ml, while LT50 extract value of Ascaridia galli and Raillietina tetragona are: 15,2 hours and 2,5 hours. The conclusion from this research is Mango arumanis leaves have anthelmintic activity.