In Vivo <i>HOXB7</i> Gene Silencing and Cotreatment with Tamoxifen for Luminal A Breast Cancer Therapy

• Main Authors: Ana Beatriz Caribé dos Santos Valle (Author), Fábio Fernando Alves da Silva (Author), Maria Ângela Pepe Carneiro (Author), Bruno Espuche (Author), Guilherme Diniz Tavares (Author), Emerson Soares Bernardes (Author), Sergio Enrique Moya (Author), Frederico Pittella (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Acquired resistance and adverse effects are some of the challenges faced by thousands of Luminal A breast cancer patients under tamoxifen (TMX) treatment. Some authors associate the overexpression of HOXB7 with TMX resistance in this molecular subtype, and the knockdown of this gene coul...