Recent Advances in the Therapeutic Efficacy of Artesunate

Artesunate, a semisynthetic artemisinin derivative, is well-known and used as the first-line drug for treating malaria. Apart from treating malaria, artesunate has also been found to have biological activity against a variety of cancers and viruses. It also exhibits antidiabetic, anti-inflammatory,...

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Main Authors: Ngonidzashe Ruwizhi (Author), Rejoice Bethusile Maseko (Author), Blessing Atim Aderibigbe (Author)
Format: Book
Published: MDPI AG, 2022-02-01T00:00:00Z.
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100 1 0 |a Ngonidzashe Ruwizhi  |e author 
700 1 0 |a Rejoice Bethusile Maseko  |e author 
700 1 0 |a Blessing Atim Aderibigbe  |e author 
245 0 0 |a Recent Advances in the Therapeutic Efficacy of Artesunate 
260 |b MDPI AG,   |c 2022-02-01T00:00:00Z. 
500 |a 10.3390/pharmaceutics14030504 
500 |a 1999-4923 
520 |a Artesunate, a semisynthetic artemisinin derivative, is well-known and used as the first-line drug for treating malaria. Apart from treating malaria, artesunate has also been found to have biological activity against a variety of cancers and viruses. It also exhibits antidiabetic, anti-inflammatory, anti-atherosclerosis, immunosuppressive activities, etc. During its administration, artesunate can be loaded in liposomes, alone or in combination with other therapeutic agents. Administration routes include intragastrical, intravenous, oral, and parenteral. The biological activity of artesunate is based on its ability to regulate some biological pathways. This manuscript reports a critical review of the recent advances in the therapeutic efficacy of artesunate. 
546 |a EN 
690 |a artesunate 
690 |a malaria 
690 |a anticancer 
690 |a tumour 
690 |a antiviral 
690 |a COVID-19 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n Pharmaceutics, Vol 14, Iss 3, p 504 (2022) 
787 0 |n https://www.mdpi.com/1999-4923/14/3/504 
787 0 |n https://doaj.org/toc/1999-4923 
856 4 1 |u https://doaj.org/article/9b652023951141dba6c1fc907fd70bf3  |z Connect to this object online.