Personalized antiplatelet therapy guided by clopidogrel pharmacogenomics in acute ischemic stroke and transient ischemic attack: A prospective, randomized controlled trial

• Main Authors: Xiaoguang Zhang (Author), Shanshan Jiang (Author), Jie Xue (Author), Ying Ding (Author), Jingyu Gu (Author), Liang Hu (Author), Xushen Xu (Author), Zhizhang Li (Author), Yuming Kong (Author), Youmei Li (Author), Xiaoqiong Zhu (Author), Yunhua Yue (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Clopidogrel is frequently used in patients with ischemic stroke or transient ischemic attack (TIA), but its efficacy is hampered by inter-individual variability, due to genetic differences associated with clopidogrel metabolism. We conducted this randomized controlled trial to validate w...