The Path from Nasal Tissue to Nasal Mucosa on Chip: Part 2-Advanced Microfluidic Nasal In Vitro Model for Drug Absorption Testing

• Principais autores: Eugen Viktor Koch (Autor), Sebastian Bendas (Autor), Kristina Nehlsen (Autor), Tobias May (Autor), Stephan Reichl (Autor), Andreas Dietzel (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2023-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The nasal mucosa, being accessible and highly vascularized, opens up new opportunities for the systemic administration of drugs. However, there are several protective functions like the mucociliary clearance, a physiological barrier which represents is a difficult obstacle for drug candidates to ove...