Dermatologic toxicity of high doses of tiothepa in children. Case report

• Main Authors: Teimur Z. Aliev (Author), Tatiana I. Potemkina (Author), Tatiana S. Belysheva (Author), Timur T. Valiev (Author), Karina A. Sergeenko (Author), Irina A. Kostareva (Author), Lana M. Kudaeva (Author), Elena B. Machneva (Author), Tatiana L. Ushakova (Author), Vladimir G. Polyakov (Author), Kirill I. Kirgizov (Author), Svetlana R. Varfolomeeva (Author)
• Format: Book
• Published: Union of pediatricians of Russia, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Hematopoietic stem cell transplantation (HSCT) is a treatment modality for a number of severe malignant and non-neoplastic diseases. Autologous hematopoietic stem cell transplantation (auto-HSCT) improves outcomes in patients with solid and hematological malignancies. Skin lesions at the auto-HSCT stage are quite common and represent an important diagnostic and therapeutic problem. The most significant causes of skin lesions in auto-HSCT are drug toxicity, infectious and viral lesions. Each of the complications can manifest itself to varying degrees as well as combine with others, having a significant negative on the patient's condition, posing a threat to the patient's life in severe cases.

Item Description

1727-5776
2500-3089
10.15690/pf.v20i2.2543