Piperlongumine inhibits neuroinflammation via regulating NF-κB signaling pathways in lipopolysaccharide-stimulated BV2 microglia cells

• Main Authors: Namkwon Kim (Author), Jimin Do (Author), Jae-sung Bae (Author), Hee Kyung Jin (Author), Jong-Ho Kim (Author), Kyung-Soo Inn (Author), Myung Sook Oh (Author), Jong Kil Lee (Author)
• Format: Book
• Published: Elsevier, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammatory processes in the central nervous system are feature among biological reactions to harmful stimuli such as pathogens and damaged cells. In resting conditions, microglia are involved in immune surveillance and brain homeostasis. However, the activation of abnormal microglia can be detrime...