<it>Brachyspira pilosicoli </it>bloodstream infections: Case report and review of the literature

<p>Abstract</p> <p><it>Brachyspira pilosicoli </it>is the etiologic agent of human and animal intestinal spirochetosis and is rarely implicated as a cause of bacteremia. Here, we describe the case of a <it>B. pilosicoli </it>spirochetemia in a 53-year-old ma...

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Main Authors: Brun-Buisson Christian (Author), Legrand Patrick (Author), Thille Arnaud (Author), Bait-Merabet Lilia (Author), Cattoir Vincent (Author)
Format: Book
Published: BMC, 2008-09-01T00:00:00Z.
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Summary:<p>Abstract</p> <p><it>Brachyspira pilosicoli </it>is the etiologic agent of human and animal intestinal spirochetosis and is rarely implicated as a cause of bacteremia. Here, we describe the case of a <it>B. pilosicoli </it>spirochetemia in a 53-year-old male patient suffering from cardiogenic shock. This fastidious bacterium was isolated from blood, likely after translocation from the intestinal tract. Blood cultures were positive after 5 days of incubation (one day after the patient's death), highlighting the problem of the recovery of such type of fastidious bacterium. Identification was achieved by molecular methods (16S rRNA sequencing). A review of the English literature found only 8 cases of bacteremia caused by <it>B. pilosicoli</it>, mostly in immunocompromised or critically ill patients. Finally, difficulties in rapid and accurate diagnosis of <it>B. pilosicoli </it>bloodstream infections, in vitro antimicrobial susceptibility of human clinical isolates, and therapeutic options are discussed.</p>
Item Description:10.1186/1476-0711-7-19
1476-0711