Selective Vulnerability of the Locus Coeruleus Noradrenergic System and its Role in Modulation of Neuroinflammation, Cognition, and Neurodegeneration
Locus coeruleus (LC) noradrenergic (NE) neurons supply the main adrenergic input to the forebrain. NE is a dual modulator of cognition and neuroinflammation. NE neurons of the LC are particularly vulnerable to degeneration both with normal aging and in neurodegenerative disorders. Consequences of th...
Saved in:
Main Authors: | Andrew K. Evans (Author), Erwin Defensor (Author), Mehrdad Shamloo (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2022-11-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Microglial Activation Mediates Noradrenergic Locus Coeruleus Neurodegeneration via Complement Receptor 3 in a Rotenone-Induced Parkinson’s Disease Mouse Model
by: Jing L, et al.
Published: (2021) -
Involvement of Locus Coeruleus Noradrenergic Neurons in Supraspinal Antinociception by α,β-Methylene-ATP in Rats
by: Masato Fukui, et al.
Published: (2004) -
Two Subpopulations of Noradrenergic Neurons in the Locus Coeruleus Complex Distinguished by Expression of the Dorsal Neural Tube Marker Pax7
by: Nicholas W. Plummer, et al.
Published: (2017) -
The Neuroanatomy of the Reticular Nucleus Locus Coeruleus in Alzheimer's Disease
by: Filippo S. Giorgi, et al.
Published: (2017) -
Phosphodiesterase-5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and Cognition
by: Christina Alves Peixoto, et al.
Published: (2015)