Anaphylactic Shock During Pediatric Anesthesia: An Unexpected Reaction to Sevoflurane

During general anesthesia, while muscle relaxants, latex and antibiotics are normally considered as very common causes of anaphylactic reactions, there are no documented cases of anaphylaxis due to inhalational agents. We report the case of a 6-year-old child scheduled for adenotonsillectomy who had...

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Main Authors: Alessandro Simonini (Author), Etrusca Brogi (Author), Brunella Gily (Author), Mariangela Tosca (Author), Claudia Barbieri (Author), Francesca Antonini (Author), Genny Del Zotto (Author)
Format: Book
Published: Frontiers Media S.A., 2018-09-01T00:00:00Z.
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100 1 0 |a Alessandro Simonini  |e author 
700 1 0 |a Etrusca Brogi  |e author 
700 1 0 |a Brunella Gily  |e author 
700 1 0 |a Mariangela Tosca  |e author 
700 1 0 |a Claudia Barbieri  |e author 
700 1 0 |a Francesca Antonini  |e author 
700 1 0 |a Genny Del Zotto  |e author 
245 0 0 |a Anaphylactic Shock During Pediatric Anesthesia: An Unexpected Reaction to Sevoflurane 
260 |b Frontiers Media S.A.,   |c 2018-09-01T00:00:00Z. 
500 |a 2296-2360 
500 |a 10.3389/fped.2018.00236 
520 |a During general anesthesia, while muscle relaxants, latex and antibiotics are normally considered as very common causes of anaphylactic reactions, there are no documented cases of anaphylaxis due to inhalational agents. We report the case of a 6-year-old child scheduled for adenotonsillectomy who had an anaphylactic shock reaction due to Sevoflurane. Several allergic tests were performed to detect the trigger. Drugs used during operation were tested on both patient and three matched controls. While controls were negative, the patient displayed a positive reaction to Sevoflurane. To our knowledge, this is the first published report describing an allergic reaction caused by a volatile anesthetic. 
546 |a EN 
690 |a Sevoflurane 
690 |a anaphylaxis 
690 |a anaphylactic shock 
690 |a allergy 
690 |a perioperative complications 
690 |a pediatric anesthesia 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pediatrics, Vol 6 (2018) 
787 0 |n https://www.frontiersin.org/article/10.3389/fped.2018.00236/full 
787 0 |n https://doaj.org/toc/2296-2360 
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