Physicochemical evaluation and in vitro release studies on itraconazolium sulfate salt

• मुख्य लेखकों: Neeraj Kumar (लेखक), Shishu Goindi (लेखक), Gulshan Bansal (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2014-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

To counter the poor aqueous solubility of itraconazole (ITC), its sulfate salt (ITCSUL) was synthesized and characterized by 1H NMR, MS, FTIR, DSC, XRPD, DLS and SEM. Antifungal properties of ITCSUL were confirmed against different fungal pathogens by broth microdilution method. Enhanced solubility...