Amphetamine Induces Oxidative Stress, Glial Activation and Transient Angiogenesis in Prefrontal Cortex via AT1-R

• Main Authors: Osvaldo M. Basmadjian (Author), Victoria B. Occhieppo (Author), Natalia A. Marchese (Author), M. Jazmin Silvero C. (Author), María Cecilia Becerra (Author), Gustavo Baiardi (Author), Claudia Bregonzio (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Amphetamine (AMPH) alters neurons, glia and microvessels, which affects neurovascular unit coupling, leading to disruption in brain functions such as attention and working memory. Oxidative stress plays a crucial role in these alterations. The angiotensin type I receptors (AT1-R) mediate...