Synchronous BRCA2 positive ovarian carcinoma with ALK positive NSCLC: Double trouble
Lung cancer being a molecularly distinct entity in the female population, multiple primary tumors including the genital and urinary tract malignancies with lung carcinoma is rare and constitutes a unique set of patient population. This case report serves to illustrate the rarity of multiple primary...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2022-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Lung cancer being a molecularly distinct entity in the female population, multiple primary tumors including the genital and urinary tract malignancies with lung carcinoma is rare and constitutes a unique set of patient population. This case report serves to illustrate the rarity of multiple primary tumor involving ovarian carcinoma with ALK positive lung cancer. Additionally high throughput sequencing revealed a germline BRCA2 mutation causing alteration of splice site. This report highlights the occurrence of multiple primary tumors in this patient possibly due to BRCA2 predisposition. |
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| Item Description: | 2772-736X 10.1016/j.hpr.2022.300667 |