Assessment of Diverse Solid−State Accelerated Autoxidation Methods for Droperidol
The present study aimed to investigate methods for accelerating autoxidation of crystalline drugs in the solid-state that can potentially predict real−time stability. Solid droperidol (DPD) was selected as the model drug. A common free−radical initiator, 2,2'−azobisisobutyronitrile (AIBN), was...
Saved in:
Main Authors: | Jayant Iyer (Author), Isha Saraf (Author), Andrew Ray (Author), Michael Brunsteiner (Author), Amrit Paudel (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2022-05-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Screening Autoxidation Propensities of Drugs in the Solid-State Using PVP and in the Solution State Using N-Methyl Pyrrolidone
by: Jayant Iyer, et al.
Published: (2023) -
Amorphous Solid Dispersions: Implication of Method of Preparation and Physicochemical Properties of API and Excipients
by: Varun Kushwah, et al.
Published: (2024) -
Relative Contributions of Solubility and Mobility to the Stability of Amorphous Solid Dispersions of Poorly Soluble Drugs: A Molecular Dynamics Simulation Study
by: Michael Brunsteiner, et al.
Published: (2018) -
PVP-H<sub>2</sub>O<sub>2</sub> Complex as a New Stressor for the Accelerated Oxidation Study of Pharmaceutical Solids
by: Dattatray Modhave, et al.
Published: (2019) -
Autoxidation Enhances Anti-Amyloid Potential of Flavone Derivatives
by: Andrius Sakalauskas, et al.
Published: (2021)